| EC |
1.1.1.388 |
| Accepted name: |
glucose-6-phosphate dehydrogenase (NAD+) |
| Reaction: |
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+
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| Other name(s): |
Glc6PDH; azf (gene name); archaeal zwischenferment |
| Systematic name: |
D-glucose-6-phosphate:NAD+ 1-oxidoreductase |
| Comments: |
The enzyme catalyses a step of the pentose phosphate pathway. The enzyme from the archaeon Haloferax volcanii is specific for NAD+. cf. EC 1.1.1.363, glucose-6-phosphate dehydrogenase [NAD(P)+] and EC 1.1.1.49, glucose-6-phosphate dehydrogenase (NADP+). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Pickl, A. and Schonheit, P. The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase--The archaeal Zwischenferment. FEBS Lett. 589 (2015) 1105–1111. [DOI] [PMID: 25836736] |
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| [EC 1.1.1.388 created 2015] |
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