| EC |
2.1.1.217 |
| Accepted name: |
tRNA (adenine22-N1)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + adenine22 in tRNA = S-adenosyl-L-homocysteine + N1-methyladenine22 in tRNA |
| Other name(s): |
TrmK; YqfN; Sp1610 (gene name); tRNA: m1A22 methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:tRNA (adenine22-N1)-methyltransferase |
| Comments: |
The enzyme specifically methylates adenine22 in tRNA. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ta, H.M. and Kim, K.K. Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine. Protein Sci. 19 (2010) 617–624. [DOI] [PMID: 20052680] |
| 2. |
Roovers, M., Kaminska, K.H., Tkaczuk, K.L., Gigot, D., Droogmans, L. and Bujnicki, J.M. The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK). Nucleic Acids Res. 36 (2008) 3252–3262. [DOI] [PMID: 18420655] |
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| [EC 2.1.1.217 created 2011 (EC 2.1.1.36 created 1972, part transferred 2011 to EC 2.1.1.217)] |
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