| EC |
2.1.1.28 |
| Accepted name: |
phenylethanolamine N-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine |
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For diagram of dopa biosynthesis, click here |
| Other name(s): |
noradrenaline N-methyltransferase; noradrenalin N-methyltransferase; norepinephrine methyltransferase; norepinephrine N-methyltransferase; phenethanolamine methyltransferase; phenethanolamine N-methyltransferase |
| Systematic name: |
S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase |
| Comments: |
Acts on various phenylethanolamines; converts noradrenaline into adrenaline. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9037-68-7 |
| References: |
| 1. |
Axelrod, J. Purification and properties of phenylethanolamine-N-methyl transferase. J. Biol. Chem. 237 (1962) 1657–1660. [PMID: 13863458] |
| 2. |
Connett, R.J. and Kirschner, N. Purification and properties of bovine phenylethanolamine N-methyltransferase. J. Biol. Chem. 245 (1970) 329–334. [PMID: 5412063] |
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| [EC 2.1.1.28 created 1972] |
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