ExplorEnz: EC 4.1.1.127

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4.1.1.127

Accepted name:

carboxyaminopropylagmatine decarboxylase

Reaction:

N¹-[(S)-3-amino-3-carboxypropyl]agmatine = N¹-(3-aminopropyl)agmatine + CO₂

Glossary:

N¹-[(S)-3-amino-3-carboxypropyl]agmatine = carboxyaminopropylagmatine
N¹-(3-aminopropyl)agmatine = aminopropylagmatine

Other name(s):

sll0873 (locus name)

Systematic name:

N¹-[(S)-3-amino-3-carboxypropyl]agmatine carboxy-lyase

Comments:

A pyridoxal 5′-phosphate protein. The enzyme, characterized from the cyanobacterium Synechocystis sp. PCC 6803, participates in a biosynthetic pathway for spermidine.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Xi, H., Nie, X., Gao, F., Liang, X., Li, H., Zhou, H., Cai, Y. and Yang, C. A bacterial spermidine biosynthetic pathway via carboxyaminopropylagmatine. Sci Adv 9:eadj9075 (2023). [DOI] [PMID: 37878710]

[EC 4.1.1.127 created 2024]