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Your query returned 1 entry. Printable version
EC | 4.2.3.156 | ||
Accepted name: | hydroxysqualene synthase | ||
Reaction: | presqualene diphosphate + H2O = hydroxysqualene + diphosphate | ||
For diagram of botryococcus braunii BOT22 squalene and botrycoccene biosynthesis, click here | |||
Glossary: | presqualene = {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(2E,6E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropan-1-yl}methyl hydroxysqualene = (6E,10E,12R,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-ol |
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Other name(s): | hpnC (gene name) | ||
Systematic name: | presqualene diphosphate diphosphate-lyase (adding water; hydroxyasqualene-forming) | ||
Comments: | This enzyme, isolated from the bacteria Rhodopseudomonas palustris and Zymomonas mobilis, participates, along with EC 2.5.1.103, presqualene diphosphate synthase, and EC 1.17.8.1, hydroxysqualene dehydroxylase, in the conversion of all-trans-farnesyl diphosphate to squalene. Eukaryotes achieve the same goal in a single step, catalysed by EC 2.5.1.21, squalene synthase. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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