| EC |
6.2.1.28 |
| Accepted name: |
3α,7α-dihydroxy-5β-cholestanate—CoA ligase |
| Reaction: |
ATP + (25R)-3α,7α-dihydroxy-5β-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3α,7α-dihydroxy-5β-cholestanoyl-CoA |
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For diagram of cholic-acid biosynthesis (sidechain), click here |
| Other name(s): |
3α,7α-dihydroxy-5β-cholestanoyl coenzyme A synthetase; DHCA-CoA ligase; 3α,7α-dihydroxy-5β-cholestanate:CoA ligase (AMP-forming) |
| Systematic name: |
(25R)-3α,7α-dihydroxy-5β-cholestan-26-oate:CoA ligase (AMP-forming) |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 118732-03-9 |
| References: |
| 1. |
Prydz, K., Kase, B.F., Björkhem, I. and Pedersen, J.I. Subcellular localization of 3α,7α-dihydroxy- and 3α,7α,12α-trihydroxy-5β-cholestanoyl-coenzyme A ligase(s) in rat liver. J. Lipid Res. 29 (1988) 997–1004. [PMID: 3183523] |
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| [EC 6.2.1.28 created 1992] |
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