EC |
1.1.1.410 |
Accepted name: |
D-erythronate 2-dehydrogenase |
Reaction: |
D-erythronate + NAD+ = 2-dehydro-D-erythronate + NADH + H+ |
Glossary: |
D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate
2-dehydro-D-erythronate = (3R)-3,4-dihydroxy-2-oxobutanoate |
Other name(s): |
denD (gene name) |
Systematic name: |
D-erythronate:NAD+ 2-oxidoreductase |
Comments: |
The enzyme, characterized from bacteria, is involved in D-erythronate catabolism. |
References: |
1. |
Zhang, X., Carter, M.S., Vetting, M.W., San Francisco, B., Zhao, S., Al-Obaidi, N.F., Solbiati, J.O., Thiaville, J.J., de Crecy-Lagard, V., Jacobson, M.P., Almo, S.C. and Gerlt, J.A. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proc. Natl. Acad. Sci. USA 113 (2016) E4161–E4169. [PMID: 27402745] |
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[EC 1.1.1.410 created 2017] |
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EC |
5.3.1.35 |
Accepted name: |
2-dehydrotetronate isomerase |
Reaction: |
(1) 2-dehydro-L-erythronate = 3-dehydro-L-erythronate (2) 2-dehydro-D-erythronate = 3-dehydro-D-erythronate |
Glossary: |
L-erythronate = (2S,3S)-2,3,4-trihydroxybutanoate
D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate |
Other name(s): |
otnI (gene name) |
Systematic name: |
2-dehydrotetronate isomerase |
Comments: |
The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism. |
References: |
1. |
Zhang, X., Carter, M.S., Vetting, M.W., San Francisco, B., Zhao, S., Al-Obaidi, N.F., Solbiati, J.O., Thiaville, J.J., de Crecy-Lagard, V., Jacobson, M.P., Almo, S.C. and Gerlt, J.A. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proc. Natl. Acad. Sci. USA 113 (2016) E4161–E4169. [PMID: 27402745] |
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[EC 5.3.1.35 created 2017] |
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