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Your query returned 5 entries. Printable version
EC | 2.1.1.339 | ||||||
Accepted name: | xanthohumol 4-O-methyltransferase | ||||||
Reaction: | S-adenosyl-L-methionine + xanthohumol = S-adenosyl-L-homocysteine + 4-O-methylxanthohumol | ||||||
For diagram of xanthohumol biosynthesis, click here | |||||||
Glossary: | xanthohumol = 2′,4,4′-trihydroxy-6′-methoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one 4-O-methylxanthohumol =2′,4′-dihydroxy-4,6′-dimethoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one |
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Other name(s): | OMT2 (ambiguous); S-adenosyl-L-methionine:xanthohumol 4′-O-methyltransferase (incorrect); xanthohumol 4′-O-methyltransferase (incorrect) | ||||||
Systematic name: | S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase | ||||||
Comments: | The enzyme from hops (Humulus lupulus) has a broad substrate specificity. The best substrates in vitro are resveratrol, desmethylxanthohumol, naringenin chalcone and isoliquiritigenin. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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EC | 2.3.1.74 | ||||||
Accepted name: | chalcone synthase | ||||||
Reaction: | 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2 | ||||||
For diagram of chalcone and stilbene biosynthesis, click here | |||||||
Glossary: | phloretin = 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one | ||||||
Other name(s): | naringenin-chalcone synthase; flavanone synthase; 6′-deoxychalcone synthase; chalcone synthetase; DOCS; CHS | ||||||
Systematic name: | malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing) | ||||||
Comments: | The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 56803-04-4 | ||||||
References: |
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EC | 2.3.1.156 | ||||||
Accepted name: | phloroisovalerophenone synthase | ||||||
Reaction: | (1) isovaleryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisovalerophenone (2) isobutyryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisobutyrophenone |
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For diagram of polyketides biosynthesis, click here | |||||||
Glossary: | phlorisobutyrophenone = 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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Other name(s): | valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase; acylphloroglucinol synthase; isovaleryl-CoA:malonyl-CoA acyltransferase | ||||||
Systematic name: | acyl-CoA:malonyl-CoA acyltransferase | ||||||
Comments: | Closely related to EC 2.3.1.74, naringenin-chalcone synthase. Also acts on isobutyryl-CoA as substrate to give phlorisobutyrophenone. The products are intermediates in the biosynthesis of the bitter acids in hops (Humulus lupulus) and glucosides in strawberry (Fragaria X ananassa). It is also able to generate naringenin chalcone from 4-coumaroyl-CoA. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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EC | 2.4.1.286 | ||||||
Accepted name: | chalcone 4′-O-glucosyltransferase | ||||||
Reaction: | (1) UDP-α-D-glucose + naringenin chalcone = UDP + 2′,4,4′,6′-tetrahydroxychalcone 4′-O-β-D-glucoside (2) UDP-α-D-glucose + 2′,3,4,4′,6′-pentahydroxychalcone = UDP + 2′,3,4,4′,6′-pentahydroxychalcone 4′-O-β-D-glucoside |
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For diagram of aureusidin biosynthesis, click here | |||||||
Glossary: | naringenin chalcone = 2′,4,4′,6′-tetrahydroxychalcone = 3-(4-hydroxyphemyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one |
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Other name(s): | 4′CGT | ||||||
Systematic name: | UDP-α-D-glucose:2′,4,4′,6′-tetrahydroxychalcone 4′-O-β-D-glucosyltransferase | ||||||
Comments: | Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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EC | 2.5.1.136 | ||||||
Accepted name: | 2-acylphloroglucinol 4-prenyltransferase | ||||||
Reaction: | prenyl diphosphate + a 2-acylphloroglucinol = diphosphate + a 2-acyl-4-prenylphloroglucinol | ||||||
Glossary: | naringenin chalcone = 2′,4,4′,6′-tetrahydroxychalcone = 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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Other name(s): | PT-1 (gene name); PT1L (gene name); aromatic prenyltransferase (ambiguous); dimethylallyl-diphosphate:2-acylphloroglucinol 4-dimethylallyltransferase | ||||||
Systematic name: | prenyl-diphosphate:2-acylphloroglucinol 4-prenyltransferase | ||||||
Comments: | The enzyme, characterized from hop (Humulus lupulus), acts on phlorisovalerophenone, phlormethylbutanophenone, and phlorisobutanophenone during the synthesis of bitter acids. It also acts with much lower activity on naringenin chalcone. Forms a complex with EC 2.5.1.137, 2-acyl-4-prenylphloroglucinol 6-prenyltransferase, which catalyses additional prenylation reactions. Requires Mg2+. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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