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Your query returned 2 entries. Printable version
EC | 1.14.19.50 | ||||
Accepted name: | noroxomaritidine synthase | ||||
Reaction: | (1) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aR,10bS)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O (2) 4′-O-methylnorbelladine + [reduced NADPH—hemoprotein reductase] + O2 = (4aS,10bR)-noroxomaritidine + [oxidized NADPH—hemoprotein reductase] + 2 H2O |
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For diagram of noroxomaritidine biosynthesis, click here | |||||
Glossary: | 4′-O-methylnorbelladine = 5-({[2-(4-hydroxyphenyl)ethyl]amino}methyl)-2-methoxyphenol noroxomaritidine = 8-hydroxy-9-methoxy-4,4a-dihydro-3H,6H-5,10b-ethanophenanthridin-3-one |
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Other name(s): | CYP96T1 (gene name) | ||||
Systematic name: | 4′-O-methylnorbelladine,NADPH—hemoprotein reductase:oxygen oxidoreductase (noroxomaritidine-forming) | ||||
Comments: | A P-450 (heme-thiolate) enzyme. The enzyme, characterized from Narcissus pseudonarcissus (daffodil), forms the two enantiomers of the Amaryllidacea alkaloid noroxomaritidine by catalysing intramolecular oxidative para-para′ phenol coupling. The oxidation involves molecular oxygen without its incorporation into the product. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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EC | 2.1.1.336 | ||||
Accepted name: | norbelladine O-methyltransferase | ||||
Reaction: | S-adenosyl-L-methionine + norbelladine = S-adenosyl-L-homocysteine + 4′-O-methylnorbelladine | ||||
For diagram of noroxomaritidine biosynthesis, click here | |||||
Glossary: | norbelladine = 4-({[2-(4-hydroxyphenyl)ethyl]amino}methyl)benzene-1,2-diol 4′-O-methylnorbelladine = 5-({[2-(4-hydroxyphenyl)ethyl]amino}methyl)-2-methoxyphenol |
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Other name(s): | N4OMT1 (gene name) | ||||
Systematic name: | S-adenosyl-L-methionine:norbelladine O-methyltransferase | ||||
Comments: | The enzyme, characterized from the plants Nerine bowdenii and Narcissus pseudonarcissus (daffodil), participates in the biosynthesis of alkaloids produced by plants that belong to the Amaryllidaceae family. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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