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Your query returned 9 entries. Printable version
EC | 1.14.19.75 | ||||||||||||||
Accepted name: | very-long-chain acyl-lipid ω-9 desaturase | ||||||||||||||
Reaction: | (1) 1-hexacosanoyl-2-acyl-[phosphoglycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = 1-[(17Z)-hexacos-17-enoyl]-2-acyl-[phosphoglycerolipid] + 2 ferricytochrome b5 + 2 H2O (2) 1-tetracosanoyl-2-acyl-[phosphoglycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = 1-[(15Z)-tetracos-15-enoyl]-2-acyl-[phosphoglycerolipid] + 2 ferricytochrome b5 + 2 H2O |
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Other name(s): | ADS2 (gene name) | ||||||||||||||
Systematic name: | very-long-chain acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase (ω9,ω8-cis-dehydrogenating) | ||||||||||||||
Comments: | The enzyme, characterized from the plant Arabidopsis thaliana, acts on both 24:0 and 26:0 fatty acids, introducing a cis double bond at a position 9 carbons from the methyl end. These very-long-chain fatty acids are found as a minor component of seed lipids, but also in the membrane phosphatidylethanolamine and phosphatidylserine, in sphingolipids, as precursors and components of cuticular and epicuticular waxes, and in suberin. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||||
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EC | 2.3.1.42 | ||||||||||||||
Accepted name: | glycerone-phosphate O-acyltransferase | ||||||||||||||
Reaction: | acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate | ||||||||||||||
Glossary: | glycerone phosphate = dihydroxyacetone phosphate = 3-hydroxy-2-oxopropyl phosphate | ||||||||||||||
Other name(s): | dihydroxyacetone phosphate acyltransferase (ambiguous) | ||||||||||||||
Systematic name: | acyl-CoA:glycerone-phosphate O-acyltransferase | ||||||||||||||
Comments: | A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37257-19-5 | ||||||||||||||
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EC | 2.3.1.251 | ||||||||||||||
Accepted name: | lipid IVA palmitoyltransferase | ||||||||||||||
Reaction: | (1) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + hexa-acyl lipid A = 2-acyl-sn-glycero-3-phosphocholine + hepta-acyl lipid A (2) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IIA = 2-acyl-sn-glycero-3-phosphocholine + lipid IIB (3) 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA = 2-acyl-sn-glycero-3-phosphocholine + lipid IVB |
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For diagram of lipid IVB biosynthesis, click here | |||||||||||||||
Glossary: | palmitoyl = hexadecanoyl hexa-acyl lipid A = 2-deoxy-2-[(3R)-3-(tetradecanoyloxy)tetradecanamido]-3-O-[(3R)-3-(dodecanoyloxy)tetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-hydroxytetradecanamido]-α-D-glucopyranosyl phosphate hepta-acyl lipid A = 2-deoxy-2-[(3R)-3-(tetradecanoyloxy)tetradecanamido]-3-O-[(3R)-3-(dodecanoyloxy)tetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-(hexadecanoyloxy)tetradecanamido]-α-D-glucopyranosyl phosphate lipid IIA = 4-amino-4-deoxy-β-L-arabinopyranosyl 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-hydroxytetradecanamido]-α-D-glucopyranose phosphate lipid IIB = 4-amino-4-deoxy-β-L-arabinopyranosyl 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-(hexadecanoyloxy)tetradecanamido]-α-D-glucopyranosyl phosphate lipid IVA = 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-hydroxytetradecanamido]-α-D-glucopyranose phosphate lipid IVB = 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phospho-β-D-glucopyranosyl-(1→6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[(3R)-3-(hexadecanoyloxy)tetradecanamido]-α-D-glucopyranosyl phosphate |
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Other name(s): | PagP; crcA (gene name) | ||||||||||||||
Systematic name: | 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid-IVA palmitoyltransferase | ||||||||||||||
Comments: | Isolated from the bacteria Escherichia coli and Salmonella typhimurium. The enzyme prefers phosphatidylcholine with a palmitoyl group at the sn-1 position and palmitoyl or stearoyl groups at the sn-2 position. There is some activity with corresponding phosphatidylserines but only weak activity with other diacylphosphatidyl compounds. The enzyme also acts on Kdo-(2→4)-Kdo-(2→6)-lipid IVA. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||||
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EC | 2.7.8.8 | ||||||||||||||
Accepted name: | CDP-diacylglycerol—serine O-phosphatidyltransferase | ||||||||||||||
Reaction: | CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine | ||||||||||||||
Other name(s): | phosphatidylserine synthase; CDPdiglyceride-serine O-phosphatidyltransferase; PS synthase; cytidine 5′-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase; phosphatidylserine synthetase; CDP-diacylglycerol-L-serine O-phosphatidyltransferase; cytidine diphosphoglyceride-serine O-phosphatidyltransferase; CDP-diglyceride-L-serine phosphatidyltransferase; CDP-diglyceride:serine phosphatidyltransferase; cytidine 5′-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase; CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase | ||||||||||||||
Systematic name: | CDP-diacylglycerol:L-serine 3-sn-phosphatidyltransferase | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9068-48-8 | ||||||||||||||
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EC | 2.7.8.29 | ||||||||||||||
Accepted name: | L-serine-phosphatidylethanolamine phosphatidyltransferase | ||||||||||||||
Reaction: | L-1-phosphatidylethanolamine + L-serine = L-1-phosphatidylserine + ethanolamine | ||||||||||||||
Other name(s): | phosphatidylserine synthase 2; serine-exchange enzyme II; PTDSS2 (gene name) | ||||||||||||||
Systematic name: | L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase | ||||||||||||||
Comments: | This mammalian enzyme catalyses an exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||||
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EC | 3.1.1.111 | ||||||||||||||
Accepted name: | phosphatidylserine sn-1 acylhydrolase | ||||||||||||||
Reaction: | (1) a phosphatidylserine + H2O = a 2-acyl-1-lyso-phosphatidylserine + a fatty acid (2) a 1-acyl-2-lyso-phosphatidylserine + H2O = glycerophosphoserine + a fatty acid |
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Glossary: | phosphatidylserine = 3-sn-phosphatidyl-L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine glycerophosphoserine = sn-glycero-3-phospho-L-serine |
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Other name(s): | phosphatidylserine-specific phospholipase A1; PS-PLA1; PLA1A (gene name) | ||||||||||||||
Systematic name: | 3-sn-phosphatidyl-L-serine sn-1 acylhydrolase | ||||||||||||||
Comments: | The enzyme, which has been described from mammals, is specific for phosphatidylserine and 2-lysophosphatidylserine, and does not act on phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid or phosphatidylinositol. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||||
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EC | 3.6.3.1 | ||||||||||||||
Transferred entry: | phospholipid-translocating ATPase. Now EC 7.6.2.1, P-type phospholipid transporter | ||||||||||||||
EC | 4.1.1.65 | ||||||||||||||
Accepted name: | phosphatidylserine decarboxylase | ||||||||||||||
Reaction: | phosphatidyl-L-serine = phosphatidylethanolamine + CO2 | ||||||||||||||
Other name(s): | PS decarboxylase; phosphatidyl-L-serine carboxy-lyase | ||||||||||||||
Systematic name: | phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming) | ||||||||||||||
Comments: | The enzyme contains a tightly-bound pyruvoyl cofactor. | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9054-78-8 | ||||||||||||||
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EC | 7.6.2.1 | ||||||||||||||
Accepted name: | P-type phospholipid transporter | ||||||||||||||
Reaction: | ATP + H2O + phospholipid[side 1] = ADP + phosphate + phospholipid[side 2] | ||||||||||||||
Other name(s): | Mg2+-ATPase (ambiguous); flippase (ambiguous); aminophospholipid-transporting ATPase (ambiguous); phospholipid-translocating ATPase (ambiguous); phospholipid-transporting ATPase (ambiguous) | ||||||||||||||
Systematic name: | ATP phosphohydrolase (P-type, phospholipid-flipping) | ||||||||||||||
Comments: | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Different forms of the enzyme move phospholipids such as phosphatidylcholine, lyso-phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidyglycerol, sphingomyelin and glucosylceramide from one membrane face to the other (‘flippase’). | ||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||||
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