EC |
1.1.1.60 |
Accepted name: |
2-hydroxy-3-oxopropionate reductase |
Reaction: |
D-glycerate + NAD(P)+ = 2-hydroxy-3-oxopropanoate + NAD(P)H + H+ |
Other name(s): |
tartronate semialdehyde reductase; (R)-glycerate:NAD(P)+ oxidoreductase |
Systematic name: |
D-glycerate:NAD(P)+ oxidoreductase |
Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9028-68-6 |
References: |
1. |
Gotto, A.M. and Kornberg, H.L. The metabolism of C2 compounds in micro-organisms. 7. Preparation and properties of crystalline tartronic semialdehyde reductase. Biochem. J. 81 (1961) 273–284. [PMID: 13900766] |
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[EC 1.1.1.60 created 1965] |
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EC |
2.3.1.106 |
Accepted name: |
tartronate O-hydroxycinnamoyltransferase |
Reaction: |
sinapoyl-CoA + 2-hydroxymalonate = CoA + sinapoyltartronate |
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For diagram of reaction, click here |
Glossary: |
sinapate = 4-hydroxy-3,5-dimethoxycinnamate
tartronate = 2-hydroxymalonate |
Other name(s): |
tartronate sinapoyltransferase; hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase |
Systematic name: |
sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase |
Comments: |
4-Coumaroyl-CoA (4-hydroxycinnamoyl-CoA), caffeoyl-CoA (3,4-dihydroxycinnamoyl-CoA) and feruloyl-CoA (4-hydroxy-3-methoxycinnamoyl-CoA) can also act as donors for the enzyme from the mung bean (Vigna radiata). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 102484-57-1 |
References: |
1. |
Strack, D., Ruhoff, R. and Gräwe, W. Hydroxycinnamoyl-Coenzyme-A-tartronate hydroxycinnamoyltransferase in protein preparations from mung bean. Phytochemistry 25 (1986) 833–837. |
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[EC 2.3.1.106 created 1989, modified 1990, modified 2002] |
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EC |
4.1.1.47 |
Accepted name: |
tartronate-semialdehyde synthase |
Reaction: |
2 glyoxylate = 2-hydroxy-3-oxopropanoate + CO2 |
Glossary: |
2-hydroxy-3-oxopropanoate = tartronate semialdehyde |
Other name(s): |
tartronate semialdehyde carboxylase; glyoxylate carbo-ligase; glyoxylic carbo-ligase; hydroxymalonic semialdehyde carboxylase; tartronic semialdehyde carboxylase; glyoxalate carboligase; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming) |
Systematic name: |
glyoxylate carboxy-lyase (dimerizing; 2-hydroxy-3-oxopropanoate-forming) |
Comments: |
A flavoprotein. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9027-24-1 |
References: |
1. |
Gupta, N.K. and Vennesland, B. Glyoxylate carboligase of Escherichia coli: a flavoprotein. J. Biol. Chem. 239 (1964) 3787–3789. [PMID: 14257608] |
2. |
Krakow, G. and Barkulis, S.S. Conversion of glyoxylate to hydroxypyruvate by extracts of Escherichia coli. Biochim. Biophys. Acta 21 (1956) 593–594. [DOI] [PMID: 13363977] |
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[EC 4.1.1.47 created 1972] |
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EC |
4.1.1.54 |
Accepted name: |
dihydroxyfumarate decarboxylase |
Reaction: |
dihydroxyfumarate = 2-hydroxy-3-oxopropanoate + CO2 |
Glossary: |
2-hydroxy-3-oxopropanoate = tartronate semialdehyde |
Other name(s): |
dihydroxyfumarate carboxy-lyase; dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming) |
Systematic name: |
dihydroxyfumarate carboxy-lyase (2-hydroxy-3-oxopropanoate-forming) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37289-51-3 |
References: |
1. |
Fukumaga, K. Metabolism of dihydroxyfumarate, hydroxypyruvate, and their related compounds. I. Enzymic formation of xylulose in liver. J. Biochem. (Tokyo) 47 (1960) 741–754. |
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[EC 4.1.1.54 created 1972] |
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EC |
4.1.2.20 |
Accepted name: |
2-dehydro-3-deoxyglucarate aldolase |
Reaction: |
2-dehydro-3-deoxy-D-glucarate = pyruvate + 2-hydroxy-3-oxopropanoate |
Glossary: |
2-hydroxy-3-oxopropanoate = tartronate semialdehyde
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Other name(s): |
2-keto-3-deoxyglucarate aldolase; α-keto-β-deoxy-D-glucarate aldolase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase; 2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming) |
Systematic name: |
2-dehydro-3-deoxy-D-glucarate 2-hydroxy-3-oxopropanoate-lyase (pyruvate-forming) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37290-56-5 |
References: |
1. |
Fish, D.C. and Blumenthal, H.J. 2-Keto-3-deoxy-D-glucarate aldolase. Methods Enzymol. 9 (1966) 529–534. |
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[EC 4.1.2.20 created 1961 as EC 4.1.2.8, transferred 1972 to EC 4.1.2.20] |
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EC |
5.3.1.22 |
Accepted name: |
hydroxypyruvate isomerase |
Reaction: |
hydroxypyruvate = 2-hydroxy-3-oxopropanoate |
Glossary: |
2-hydroxy-3-oxopropanoate = tartronate semialdehyde
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Systematic name: |
hydroxypyruvate aldose-ketose-isomerase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 74812-48-9 |
References: |
1. |
De Windt, F.E. and van der Drift, D. Purification and some properties of hydroxypyruvate isomerase of Bacillus fastidiosus. Biochim. Biophys. Acta 613 (1980) 556–562. [DOI] [PMID: 7448201] |
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[EC 5.3.1.22 created 1983] |
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